The Supercentenarian Research Foundation (SRF) is a
scientifically based, non-profit international organization that funds long term research
into the factors controlling human aging in order to increase healthy human life span to
the maximum extent possible. It will also serve as a think tank to illuminate factors
involved in aging and longevity.
Initially the sponsored research will focus on diagnosing the causes and effects of
morbidity and mortality down to the cellular and molecular level in those who are 110
years old or more. In addition our research will attempt to determine the genetic and
physiologic characteristics of supercentenarians that have enabled them to overcome,
delay, or escape the age-associated diseases that are the common causes of death of those
who are unable to reach such an advanced age. Because nature has performed a human
experiment in which only a few survive to extreme old age, examination of their genetics
may reveal a common genotype that is not present in the general population. Study of
siblings and children of supercentenarians will be performed concomitantly with that of
their elderly relatives. As progress in research develops, successive stepwise
investigation of younger groups will also be conducted. When the causes and effects of
aging become clearer, research will be directed toward developing interventions to
prevent, ameliorate, and reverse those effects.
The goal of the SRF is to contribute multi-hundred million dollars in grants for
scientific research into the aging process within 10 years.
Throughout its existence the SRF will seek to further the cause of extension of healthy
life span by cooperation with private, public, governmental, and commercial entities. Data
collected will be made as widely available as possible. The combined effort of the
Directors and officers of the SRF, members of the SRF, the scientific community,
supercentenarians and their families, and the financial sponsors is absolutely essential
to the success of the SRF. Acceptance by the public-at-large of the practical potential of
significant extension of healthy human life is an important objective of the SRF.
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